Diethyl malonate

Jeneng Produk:

Diethyl malonate

Padhanane:

Malonat Asam Diethyl Ester; Ester Malon; Ethyl Malonate; Ethyl Propijiate; FEMA 2375; Dem; Dicarbethoxymethane; Diethyl Malonate

CAS:

105-533

Mf:

C7h12O4

Mw:

160.17

EineCs:

203-305-9

Kategori Produk:

Blok bangunan; C6 nganti C7; senyawa karbony; sintesis kimia; ester; organika; blok bangunan organik

File mol:

105-53-3.mol

Titik lebur 

-50 ° C

Titik Giling 

199 ° C (lit.)

Kapadhetan 

1.055 g / ml ing 25 ° C (lit.)

Kapadhetan uap 

5.52 (vs udhara)

meksa uap 

1 mm Hg (40 ° C)

FEMA 

2375 | Diethyl malonate

Indeks Refleksi 

N20 / d 1.413 (lit.)

FP 

212 ° F

Temp panyimpenan. 

Simpen ing ngisor + 30 ° C.

kelarutan 

20.8g / l (eksternal MSDS)

PKA

13.5 (ing 25 ℃)

Formulir 

Cairan

Watesan Letupan

0.8-12.8% (v)

Kelarutan banyu 

Kesalahan karo Ethyl Alkohol, Ether, Chloroform lan Benzene. Rada salah karo banyu.

Jecfa Nomer

614

Merck 

14,3823

Brn 

774687

Stabilitas:

Stabil. Concustible. Ora kompatibel karo agen pengoksidaan sing kuwat,

Incipey

Eyxgsmugojnhaz-uhfffaoysa-n

Rujukan Database CAS

105-533-3 (Rujukan Database CAS)

Cathetan Kimia NIST

Asam propijiis, diethyl es (105-53-3)

Sistem Registri EPA

Diethyl Malonate (105-53-3)

Kode Hazard 

Xi

Pernyataan Resiko 

36/37 / 38-36

Pratelan safety 

24 / 25-26

WGK Jerman 

1

RTEK 

OO0700000

Suhu Autignition

435 ° C DIN 51794

CATETAN HAZARD 

Gerah

Tsca 

Ya

Kode hs 

29171910

Keracunan

LD50 kanthi lisan ing terwelu: 15720 mg / kg ld50 kelinci dermal> 16000 mg / kg

Properties Kimia

Cairan tanpa warna

Properties Kimia

Diethyl Malonate duwe ambu ora enak, apik banget.

Nggunakake

Pabrik barbiturates.

Preparation

Nanggepi asam kloroaketik kanggo asam sianoasetik nggunakake sodium syanida lan saponication; Asam Malonik pungkasane kepala karo distilasi azeotropik kanthi etanol ing benzene

Nilai ambang rasa

Karakteristik rasa ing 50 ppm: Manis lan fruity karo najis apel lan nanas.

Gambar Keamanan

Entheng beracun kanthi diestion. Gangguan kulit. Cairan sing bisa diobong nalika kapapar panas utawa nyala; bisa nanggepi bahan sing dioksidasi. Kanggo nglawan geni, gunakake banyu menyang geni kemul, busa, CO2, bahan kimia garing. Yen digawe panas kanggo bosok kasebut ngetokake asap akrid lan wasap sing ngganggu. Deleng uga ester.

Metode pemurnian

Yen ora pati jelas (IR, NMR) ester (250g) digawe panas ing adus uap kanggo 36 jam kanthi etoh sing mutlak (125ml), banjur fraksi sing disusupi. Yen ora, fraksi sing ora cocog ing sangisoré tekanan lan ngumpulake bagian tengahan sing gedhe banget. [BEILstein 2 IV 1881.]

Produk Preparation

2-hemyldecanoic asam -> Asam Cyclopentylic -> 5-Chlororo-Benzofuran-2-karboxxy Asam Etter -> Enxacin -> 4,6-Dichlorozone -> 4,6-benzofuranslobo -> Asam Benzofuranboxxylic, Etyl Ester - 5-nitrobenzofuran-2-karboxinic asam - 4-chlororo-2-methenesulfuran-6-METEXY-PYRIMIDINE -> etyl 7-Cartboxofuran-2-Cartboxily -> 5,7-BIS (trifluoromethyl) -4-chloroquinoline -> 2-DimethypiSpyrimidine -> Pyrimidine 4-2-METYLOYE-6- (metilthio) , 98% -> 5,7-bis (trifluoromethyl) -4-hydroxyquinoline -> 2- (trifluoromethyl) -4-carboxylicine-2-carboxylic -> 2-eothylicylic asam diethyl Ester -> 2,4-DihydroXyPyrimidine-5-Carboxylic-2,6-Dihydroxy-2-Methylpyrimidine -> 5-MethylpyRomethyline-3-Chloro-7- (Trifluoromethyl) Quinoline -> Etyl 4-Chlororo-6- (TrifLuoromethyl) -3-QuinolinCarboxy -> 4-Hydroxy-5,7-BIS-TriFluoromethyl-Quinoline Acid AthilyL-QuinxanlicAltboxilyLate -> Etyl 2- (Ethylthio) -4-Hydroxypyrimidine-5-karboinopylageticylacetic -> GLICLAFIDE-3-CARBOXTALL) Quinoline butylmalonate -> 2-aminodiethylmalonate -> 2-amino-1-chloropyrimidin-4 (3H) -one -> 3-carbethoyoxyumbeliferone -> diethyl 2- (2-syanoethyl) Malonate -> 5-Corbethoxyitacil -> 3-karbethoxy-2-piperidone -> 2-amino-amino-hydroxypyrimidin-4 (3H) -one -one, 97% -> sulfamonomethoxine

Bahan mentah

Etanol -> Asam Hydrochloric -> Sodfuric Carbonate -> Sodium Cyanide -> Asam Sirium Asam Sodium -> Asam Chloroacetic -> Asam Chlorocetic -> Asam Chlorocetic -> Asam Chlorocetic -> Asam Khloretik